TREM2 triggers microglial density and age‐related neuronal loss
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چکیده
منابع مشابه
Zinc triggers microglial activation.
Microglia are resident immune cells of the CNS. When stimulated by infection, tissue injury, or other signals, microglia assume an activated, "ameboid" morphology and release matrix metalloproteinases, reactive oxygen species, and other proinflammatory factors. This innate immune response augments host defenses, but it can also contribute to neuronal death. Zinc is released by neurons under sev...
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ژورنال
عنوان ژورنال: Glia
سال: 2018
ISSN: 0894-1491,1098-1136
DOI: 10.1002/glia.23563